Count me against the notion that almost everything in Prey 2 should be interactive.
Nope. I do feel there should be a bit more interaction with the levels but they don't need to go over the top with it. Leave that for DNF.
I'd love to see the background of Tommy explored more in the sequel and his daily life on the reservation. Perhaps how he met Jen and how their relationship developed.
More stuff with portals obviously. Alot more. What else are they capable of? What hidden secrets do they possess?
As Scott hinted at: more diverse environments. More diverse enemies. A bit longer story/game.
Spirit walking can be reworked/beefed up. Perhaps when Tommy goes into the spirit realm he now encounters enemies who are also in the spirit realm? Wraiths that try to steal his soul before he jumps back into his body? Possessing enemies to temporarily take them over(I know a few other games have done this sort of thing but I thought Prey really screamed for this feature once I heard of the spirit walking feature).
Just a few things.